miR-26a enhances autophagy to protect against ethanol-induced acute liver injury
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چکیده
منابع مشابه
Autophagy is activated to protect against endotoxic acute kidney injury
Endotoxemia in sepsis, characterized by systemic inflammation, is a major cause of acute kidney injury (AKI) in hospitalized patients, especially in intensive care unit; however the underlying pathogenesis is poorly understood. Autophagy is a conserved, cellular catabolic pathway that plays crucial roles in cellular homeostasis including the maintenance of cellular function and viability. The r...
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Although miR-150 is implicated in the regulation of immune cell differentiation and activation, it remains unknown whether miR-150 is involved in liver biology and disease. This study was performed to explore the potential role of miR-150 in LPS/D-GalN and Fas-induced liver injuries by using wild type and miR-150 knockout (KO) mice. Whereas knockout of miR-150 did not significantly alter LPS/D-...
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ژورنال
عنوان ژورنال: Journal of Molecular Medicine
سال: 2015
ISSN: 0946-2716,1432-1440
DOI: 10.1007/s00109-015-1282-2